Tuesday, May 27, 2008

Incident shows Taser may have affected heart


WASHINGTON (Reuters) - A quick shock from a Taser may have zapped a man's fluttering heart back into a healthy rhythm, doctors reported on Tuesday.
They cited the incident as evidence that the devices, which are used by police who want to use less-than-deadly force to incapacitate people but are condemned by some civil rights groups as dangerous, may affect the heart as critics allege.
In this case, the outcome was a happy one, the doctors reported in the Annals of Emergency Medicine. Several lawsuits in the United States and Canada contend the devices, which use an electric charge to subdue an attacker, can stop the heart.
The 28-year-old patient was fleeing police and jumped into a lake in April, when the water was still very cold.
"I don't know exactly what he had done but he fled capture from them and he hid in a lake," said Dr. Kyle Richards, a cardiologist at Hartford Hospital in Connecticut, who treated the man when he was taken to an emergency room.
Richards said the patient was experiencing an irregular heart rhythm known as atrial fibrillation, possibly as a result of the cold and shock.
After treatment, the patient was eager to leave. "He got very combative and started yelling in my face and that's when I left the room and got security," Richards said.
Police and security used a Taser stun gun, which shoots out a lead connected to two barbs that can deliver up to 50,000 volts. They used a low-voltage charge meant to cause pain rather than a longer, higher-voltage jolt meant to incapacitate.
The patient calmed down and another electrocardiogram showed his heart rhythm was normal
"This is the first report of a patient receiving a shock of this kind and having a positive outcome," Richards said.
Amnesty International says that since 2001 more than 290 people have died in North America in incidents involving the weapon. Taser International says there is no evidence the gun directly caused the deaths.
Richards said studies done in pigs show the weapon can affect the heart muscle.
This case provided a controlled situation, with almost continuous monitoring of the patient's heart.
Richards noted that the patient was not hooked up to the electrocardiogram at the precise moment of being shocked.
"People can spontaneously go from atrial fibrillation into a normal rhythm without any intervention at all. You cannot conclusively say that the Taser did it," he said. But he said he believed it did.
"It's just one more thing that says, hey, Tasers can actually affect the heart."

Child obesity epidemic seen leveling off


WASHINGTON (Reuters) - The U.S. childhood obesity epidemic leveled off this decade after surging for about 20 years, but a worrisome 16 percent of young people remain obese, risking serious health problems, researchers said on Tuesday.
Obesity rates remained essentially unchanged among boys and girls ages 2 to 19 from 1999 to 2006, researchers led by Cynthia Ogden of the Centers for Disease Control and Prevention wrote in the Journal of the American Medical Association.
The study found that 32 percent fit the government's definition of being overweight, 16 percent fit the definition for obesity and 11 percent were extremely obese.
Childhood obesity rates had tripled in the two decades starting in 1980, Ogden said. Changes in diet -- more fatty and sweetened foods -- and less exercise helped fuel the trend.
"The prevalence is still very high. And so it's not as if the problem is solved. But there is some reason for cautious optimism," Ogden said in a telephone interview.
The study did not show any drop in childhood obesity. And it did further illustrate ongoing racial disparities.
Dr. David Ludwig, a childhood obesity expert at Children's Hospital Boston, said it is too soon to know if the findings represent a mere temporary lull in a long-term upward trend or a true, enduring leveling off of an epidemic.
"This study is a glimmer of hope," Ludwig said in a telephone interview, saying it might show that public health efforts to increase awareness of obesity may be paying off
The researchers examined height and weight measurements for 8,165 people ages 2 to 19 taken in government surveys from 2003 through 2006, allowing them to calculate body mass index, or BMI, a measure of obesity.
GROWING PROBLEM
They compared the data with numbers dating back to 1999, finding no statistically significant differences in rates.
Childhood and adult obesity has emerged as a growing problem not only in the United States but in many countries around the world.
Obese children are more likely to be saddled with risk factors associated with cardiovascular disease such as high blood pressure and high cholesterol, as well as type 2 diabetes. They also are at higher risk for asthma.
They also are much more likely to be obese in adulthood, when they may face the many health problems linked to obesity such as heart disease, stroke, diabetes and some cancers.
The study illustrated ongoing ethnic and racial disparities.
It found that 17 percent of boys 2 to 19 overall were obese, but 23 percent of Mexican American boys were obese compared to 17 percent of blacks and 16 percent of whites. For girls, 16 percent were obese, including 24 percent of blacks, 19 percent of Mexican Americans and 14 percent of whites.
"Obesity is striking poor and minority children more severely than whites and wealthier populations," said Ludwig, who wrote an editorial in the journal to accompany the study and had a book on the subject published last year
The childhood obesity epidemic has been driven by significant changes in the U.S. diet dating back decades, with more fatty and sugary fast foods, snacks, processed foods and beverages and fewer fresh fruits and vegetables.
Many children also have become more sedentary, watching more TV, playing video games and getting less exercise

Cancer risk soars in HIV-infected people: study


WASHINGTON (Reuters) - People with HIV have a much higher risk for many cancers, including anal cancer, but a lower risk for prostate cancer, researchers said on Tuesday.
Some types of cancers like Kaposi's sarcoma and non-Hodgkin lymphoma have long been associated with people infected by the AIDS virus.
The study focused on trends from 1992 to 2003, finding that these two types of cancer became relatively less common among HIV-infected people in the United States. But other cancers are on the rise among these patients, who are living longer thanks to anti-HIV drugs.
Anal cancer by 2003 had become 59 times more common among HIV-infected people than the general population, according to the study in the Annals of Internal Medicine.
Hodgkin's disease was 18 times more common in this population, the study also found. In addition, liver cancer was seven times more common, lung cancer 3.6 times more common, the skin cancer melanoma and throat cancer both three times more common, and colorectal cancer 2.4 times more common.
The study involved 54,780 men and women infected with the human immunodeficiency virus, which causes AIDS.
It found HIV-infected people had a small reduced risk for prostate cancer. The researchers said that may be because men with HIV infections are more likely to have lower testosterone levels, which could be protective against prostate cancer.
"The study was done because we all know that now people with HIV are living longer, and HIV is looking more like a chronic disease. So we wanted to look at one of the other very large chronic killers in America, cancer," Dr. Pragna Patel of the U.S. Centers for Disease Control and Prevention, who led the study, told Reute
SCREENING IMPORTANT
Patel said doctors who care for HIV-infected people should be aware of this increased risk for a range of cancer types, and consider screening.
She called the study the largest analysis of cancer trends among HIV-infected people in the United States ever done.
The virus devastates the body's immune system, raising susceptibility to illnesses and infections. Many early AIDS patients developed Kaposi's sarcoma, a cancer previously associated with older people or people receiving immunosuppressant medications following an organ transplant.
But the advent of combination drug therapy in the 1990s called highly active antiretroviral therapy, or HAART, greatly extended the lives of many HIV-infected people, particularly in developed countries.
"Most significant was the finding of anal cancer being so elevated even in the HAART era," Patel said.
She said multiple factors may be involved, but the increased risk may be linked to the fact that anal sex by homosexual men can spread the human papillomavirus, or HPV, which is known to cause anal cancer.
"Of course, anal sex and how many times you have anal sex and how many sex partners you have -- that all matters with regard to HPV infection," Patel said.
Human papillomaviruses are common viruses that can cause warts among other things. About 30 types increase the risk for cancers, including cervical cancer. These are passed through sexual contact with an infected partner.
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Gum disease may raise cancer risk, study finds


CHICAGO (Reuters) - Gum disease may increase the risk of developing cancer, researchers said on Tuesday.
Male health professionals with a history of gum disease in a long-running study had a 14 percent higher overall risk of developing cancer, they said.
"After controlling for smoking and other risk factors, periodontal disease was significantly associated with an increased risk of lung, kidney, pancreatic and hematological (blood) cancers," Dr. Dominique Michaud of the Imperial College London and colleagues wrote in the journal Lancet Oncology.
This higher overall risk persisted even in people who had never smoked.
Gum or periodontal disease is an infection of the tissues surrounding and supporting the teeth. Prior studies have suggested people with periodontal disease are more likely to develop heart disease and diabetes.
People with gum disease have inflammation in their blood and inflammation also has been linked with cancer. But this could simply mean that whatever causes the inflammation may also cause gum disease and cancer. Michaud and colleagues wanted to see if gum disease increases the risk of cancer.
They used data from a large study of male doctors and other health professionals aged 40 to 75. The study was started in 1986 at Harvard University.
Nearly 50,000 men filled out health surveys and were followed for more than 17 years. The survey included information on gum disease and bone loss as well as number of teeth and tooth loss.
More than 5,700 of the men developed cancer, excluding cases of non-melanoma skin cancers and non-aggressive prostate cancer. The researchers found that men who had gum disease had 14 percent higher cancer risk compared to those who did नोट

The risks were higher depending on the type of cancer.
Those with history of gum disease had a 36 percent higher risk of lung cancer, a 49 percent higher risk of kidney cancer, a 54 percent higher risk of pancreatic cancer and a 30 percent higher risk of having a blood cancer (such as non-Hodgkin lymphoma, leukemia or multiple myeloma) compared to men who did not have a history of gum disease.
In those who never smoked, gum disease was linked with a 21 percent increase in overall cancer risk and a 35 percent higher risk of blood cancers. They found no association for lung cancer in this group.
Men who had fewer teeth (0 to 16) at the start of the study had a 70 percent higher risk of lung cancer compared with individuals with more teeth (25 to 32) at the start of the study but this may be linked with smoking.
"The increased risks noted for hematological, kidney, and pancreatic cancers need confirmation but suggest that gum disease might be a marker of a susceptible immune system or might directly affect cancer risk," Michaud said in a statement.
They said it is premature to suggest that good oral hygiene can have any effect at preventing cancer but said periodontal disease should nevertheless be treated.

Vitamin D doesn't cut prostate cancer risk


WASHINGTON (Reuters) - Vitamin D -- the so-called sunshine vitamin -- does not appear to cut a man's risk of getting prostate cancer, researchers said on Tuesday.
Previous studies have found protective effects from higher vitamin D levels for certain cancer types including colon and breast cancer, as well as other ailments.
U.S. National Cancer Institute researchers set out to see if vitamin D might protect against prostate cancer, the second most frequently diagnosed cancer in men worldwide. They tracked vitamin D concentrations in the blood of 749 men diagnosed with prostate cancer and 781 men who did not have the disease.
They found no association between higher levels of the vitamin and a reduced prostate cancer risk. The findings hinted at a possible increased risk for aggressive prostate cancer in men with higher blood concentration of vitamin D, but this link was not statistically significant, the researchers said.
"In our study, we didn't see any protective effect of vitamin D in relation to prostate cancer risk," Jiyoung Ahn of the U.S. National Cancer Institute, one of the researchers, said in a telephone interview.
Levels of vitamin D were measured in a blood sample provided by the men when they entered the study. Those with prostate cancer were diagnosed one to eight years after the blood samples were given, the researchers said.
Ahn, whose study was published in the Journal of the National Cancer Institute, said previous research had shown that high doses of vitamin D inhibited the growth of human prostate cancer cells in a laboratory dish.
The body makes vitamin D when skin is exposed to sunlight, thus earning its nickname the sunshine vitamin। It is found in fatty fish such as salmon and milk commonly is fortified with

Vitamin D helps the body absorb calcium and is considered important for bone health. In adults, vitamin D deficiency can lead to osteoporosis, and it can lead to rickets in children.
Some studies have indicated it might provide other benefits. For example, one study published in January found that people with low vitamin D levels had an elevated risk for heart attack, heart failure and stroke, suggesting it may protect against cardiovascular disease.
National Cancer Institute researchers found in a study published last October that people with higher vitamin D levels were less likely to die of colorectal cancer but it did not appear to affect the risk of dying from other cancer types.
But Canadian researchers reported earlier this month that women with breast cancer who had lower levels of vitamin D were more likely to die and more likely to have their cancer spread than women with normal levels of the vitamin.
The American Cancer Society estimates that about 780,000 men are diagnosed annually with prostate cancer worldwide, with about 250,000 deaths a year. The group called prostate cancer the sixth leading cause of cancer death in men worldwide.
(Editing by Maggie Fox and Bill Trott)

Mars probe sends back new pictures of landing site





























LOS ANGELES (Reuters) - The Phoenix lander has sent back new pictures from the arctic circle of Mars, showing for the first time the spot where it will dig through the Red Planet's dusty surface looking for water and assess conditions for life.
The remarkable images, displayed on Tuesday by mission managers, offered a glimpse of the Martian valley where Phoenix will scoop up samples of frozen soil for analysis by its instruments -- as well as views of the lander and its discarded parachute standing out starkly from the dark surface of the planet where they came to rest.
"This is a place we're going to get to know very well over the next three months," the mission's chief scientist, Peter Smith, said in describing the 30-mile wide valley and small hills on the horizon.
Mission managers said Phoenix, which touched gently down on Mars on Sunday after a 10-month, 420 million-mile (676 million-km) journey from Earth, had come through its landing in good shape, though they were still grappling with a pair of technical glitches.
The more serious of those involved Phoenix's inability to communicate with NASA's Mars Reconnaissance Orbiter, which, along with the Odyssey spacecraft, must relay commands and data back to Earth, since the lander cannot communicate directly with its home planet.
Fuk Li, manager of the Mars exploration program for NASA's Jet Propulsion Laboratory in Pasadena, said the problem was a UHF radio on the orbiter, which he said appeared to have shut down after an unknown "transient event" in space.
CALLING ODYSSEY
Li said the Phoenix team was working to re-establish communications and did not expect the mission to be compromised because the lander was still in contact with Odyssey।
"We would just have to ask Odyssey to work harder," Li said.
Phoenix also had trouble fully retracing a covering for its robotic arm, although managers said it appeared the arm would be able to fully function.
Phoenix touched down at 4:53 p.m. PDT on Sunday, becoming the first spacecraft to reach a polar region of Mars. Problems during descent doomed NASA's first polar lander in 1999.
Over the next three months, scientists want to bore into the ground and study water and soil samples to determine if conditions were suitable to support life. In addition to determining if the water was ever liquid, scientists want to find out if it holds any organic matter.
The Viking landers in the 1970s and early 1980s conducted similar tests on surface soils. Scientists later determined solar radiation flowing through the planet's thin atmosphere creates a sterile environment as it bombards the ground.
Subsurface conditions, however, might provide habitats for microbes and bacterial life to flourish on Mars, as they do in extreme environments on Earth.
For the past decade, NASA has been searching for signs of past water on Mars with a fleet of orbiters and a pair of rovers on the ground.
The detection of subsurface frozen water in 2002 by Mars Odyssey prompted scientists to propose the Phoenix mission. (Editing by Doina Chiacu)